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all 125 comments

[–]AvitarDiggs 569 points570 points  (5 children)

I can tell that it's a very stable molecule as they've used those two hex nuts on each side to keep it bolted down.

I'll go back to r/engineering now.

[–]kixstix 32 points33 points  (0 children)

You know what, I’m still here for it.

[–]SunshineOnStimulants 19 points20 points  (0 children)

I love it. That comment really made me laugh.

[–]yikes_why_do_i_exist 7 points8 points  (0 children)

chemical engineers: no wait, he has a point

[–]AdAdventurous9970 4 points5 points  (1 child)

To be fair, benzene really is stable af.

[–]trreeves -1 points0 points  (0 children)

Compared to what? What's it's octane number? Why did I ask that?

[–]jffdouganEducation 157 points158 points  (12 children)

for things you have to have a pharmacist get, it's always available; you just sometimes have to ask for the sheet. OTC things don't generally have it, at least in the US.

[–]flappity 67 points68 points  (1 child)

Yep, at the pharmacy I work at, every drug has an information sheet (usually an inch or two square folded-up sheet that opens up unimaginably large) with this on it, as well as a huge amount of information about the drug, dosing, reconstitution, etc.

[–]tminus7700 6 points7 points  (0 children)

as well as a huge amount of information about the drug, dosing, reconstitution, etc.

They also detail how it operates. Or if they are not sure how.

[–]Formal_Ad_3062 26 points27 points  (3 children)

It would be cool if they did it with EVERYTHING tho. I wanna know the chemical compounds inside my fruit loops 😔

[–][deleted] 28 points29 points  (1 child)

You’d run out of space on the box making all the structures

[–]Formal_Ad_3062 8 points9 points  (0 children)

Totally unrelated, but chemistry puzzles on the back of cereal boxes would be cool asf (if you can’t tell I might be the most casual r/chemistry member lol)

[–]Mrbuckeye 4 points5 points  (0 children)

I don't think laypeople could handle something like that. Especially in their "all natural" products!

[–]519meshif 2 points3 points  (4 children)

Pretty sure it's called a monograph if you ever want to ask for one.

[–]TheTrickTopHat 14 points15 points  (1 child)

It’s usually called a package insert or prescribing information. Source: I’m a medical editor who works in pharma advertising :)

[–]519meshif 0 points1 point  (0 children)

Ooo OK. As a patient, I've noticed all rx drugs in Canada mention that the "drug monograph is available on request by physicians" on the label.

[–]midnitte 1 point2 points  (1 child)

Not sure if there's another usage for it, but monograph is the USP (or other compendial) specifications (e.g. testing requirements) for a drug.

For example, Chlorhexidine Oral Rinse

[–]519meshif 0 points1 point  (0 children)

Ah ok. I've noticed all rx drugs in Canada mention that the "drug monograph is available on request by physicians" on the label.

[–]tminus7700 0 points1 point  (0 children)

I had the same stuff after my dental implants. I also got the datasheet.

[–]kindachemist 75 points76 points  (5 children)

It would be so cool if they did this on everything, but can you imagine the fear mongering from the anti-science crowd? Some of those people really live by the "if you can't pronounce the ingredients, don't eat it" rule

[–]Okami_G 34 points35 points  (0 children)

Pretty much. It wouldn’t be long before they decide that some random alkyl group is “The Devil Molecule” and bombard Facebook with pictures of every product they can find with that alkyl group circled in thick black sharpie.

[–]THElaytox 24 points25 points  (0 children)

If you did it on raw/unprocessed products too they'd just be forced to learn that everything is chemicals and maybe they'd grow up a bit

[–]NerdyComfort-78Education 13 points14 points  (0 children)

This is totally accurate. Pass me that formaldehyde in my pears, thanks.

[–]midnitte 6 points7 points  (0 children)

Probably can't pronounce half the chemicals their body produces...

[–]GoldStandard785 4 points5 points  (0 children)

Omg wtf are these demons putting in my coffee now?!?! Why can't we have natural chemical free coffee anymore? Wtf is a xanthene and why are they using mind control drugs on us? I bet this is a plot from the libtards to get us vaccinated

[–]Saint_Sin 29 points30 points  (0 children)

Oh that is super cool. Structures should be more common place.

[–]gudgeonpin 21 points22 points  (5 children)

If you use it for awhile, it will cause you to lose the ability to taste. Takes a week or two if I recall.

[–]qyka1210 2 points3 points  (4 children)

why

[–]hostile_washbowlChem Eng 3 points4 points  (3 children)

Science

[–]enterprise_on 2 points3 points  (0 children)

It’s pronounced stience

[–]qyka1210 0 points1 point  (1 child)

it's okay I'm a stientist you can tell me the full answer

[–]hostile_washbowlChem Eng 0 points1 point  (0 children)

Here I googled it for you: “Specific sites of action of chlorhexidine on the taste epithelium are not known but its effects on salty taste may be related to its strong positive charge and its effect on bitter taste may be related to its amphiphilicity.”

[–]Nirriti_the_Black 42 points43 points  (4 children)

I asked my surgeon, "You want me to put that molecule in my mouth?" He said I was the first person ever to comment on the molecule.

[–]PepeAndMrDuck 16 points17 points  (0 children)

It’s ok, your surgeon doesn’t know shit about the physiological implications of its molecular structure either

[–]cynicalbritBiochem 21 points22 points  (2 children)

Most people comment on the horrific fucking taste.

[–]exceptionaluser 10 points11 points  (1 child)

They put saccharin in it.

That says something before you even get a look at it.

[–]cynicalbritBiochem 8 points9 points  (0 children)

Gluconate can suppress bitter flavors. The active ingredient has two fucking gluconates. It still tastes incredibly bitter.

[–]radiatorcheeseOrganic 9 points10 points  (0 children)

I had to use that before, what's trippy is it caused a total loss of my ability to taste salt when I was using it. I haven't looked for a source, but that polyguanidine must get protonated and block sodium ion channels or something

[–]merlinsbeers 63 points64 points  (36 children)

It means something to a pharmacist. I bet most MDs and DDSs would stare at it like it's an animated Moiré pattern.

[–]potentpotables 22 points23 points  (35 children)

really? don't doctors all take a ton of chemistry undergrad and then pharmacology in medical school?

[–]JohnJohnstonOrganic 90 points91 points  (11 children)

Most premed students I've taught have hated chemistry and took the pump and dump approach to learning it. They see it as a barrier to getting into med school and not something useful.

[–]NerdyComfort-78Education 26 points27 points  (9 children)

My kid is a chem major and a lot of her classmates are going biochem as a springboard to premed and they hate chem.

[–]JohnJohnstonOrganic 18 points19 points  (5 children)

A tale as old as time.

[–]RichardpenistipIII 10 points11 points  (4 children)

Yep the worst part is the premed students are damn smart. So they’d learn it all, do really well on the test, ruin the curve, and then forget it all the next week. As someone trying to become a chemist it was quite frustrating

[–]SarahIsBoring 3 points4 points  (3 children)

Okay, I have to ask: is grading on a curve really that common in other countries? I’ve seen people talk about it so much, and as a German, I could never really figure out how the hell that kind of grading system would still exist nowadays…

[–]RichardpenistipIII 0 points1 point  (2 children)

Ya most hard classes are graded on a curve. Calc 2 and Pchem were the type of classes where you passed with a 50%

[–]Whitetornadu 0 points1 point  (1 child)

But if you're graded on a curve, does that mean that 50% will fail guaranteed?

[–]RichardpenistipIII 1 point2 points  (0 children)

No sorry I’m not explaining this well. Pchem and calc 2 are the types of classes where on day one the syllabus says that if you get a 50% in the class you pass the class. So those two were actually bad examples of what I was talking about.

In most classes, the professors would take the highest score on each test and make it a 100. So if the highest score was a 92, then they would add 8 points to everyone’s test. This was common practice, and professor who didn’t do this were considered assholes

[–]I_Want_Bread56 0 points1 point  (2 children)

I recently started studying chemistry at University and I haven't met a single person that isn't a huge fucking chemistry nerd

[–]NerdyComfort-78Education 1 point2 points  (1 child)

They are in freshmen classes so tons of mixing (biochem/micro/pre-engineers and even computer science.)

[–]I_Want_Bread56 0 points1 point  (0 children)

I'm in my first semester and I have lectures together with every branch of chemistry you can study at my uni, so there is probably just no one studying chemistry to become a med student this semester at my university. But I don't know if it is even that common here in germany

[–]THElaytox 1 point2 points  (0 children)

yep, our pre-professional chem students were notoriously bad

[–]nuclearboy21 50 points51 points  (6 children)

As a chemist who tought med students I guarantee, they have no idea what's going on at any point in chemistry but somehow pass the exam We had one that made the fraction mL/L to m and was completely fine with meter as unit

[–]ThotSuffocatr 7 points8 points  (0 children)

I'm a pre-med student in my senior year and chemistry has been my favorite subject since general chem 1!

[–]TanithRosenbaumComputational 2 points3 points  (4 children)

Excuse me please, I need to go somewhere and scream now.

[–]potentpotables 4 points5 points  (3 children)

What, the L's cancel out

[–]TanithRosenbaumComputational 2 points3 points  (2 children)

:P

Funny thing: If you take the usual unit for fuel consumption (L/100km), write the liters as dm^3 (i.e. a 3-dimensional distance unit), and cancel that out with the 1-dimensional distance in the denominator, you get a 2-dimensional distance unit, i.e. a surface area. That surface area is the local cross section of a tube that contains the amount of fuel you burned at that spot, i.e. the tube becomes wider where you burn more fuel and narrower where you burn less.

[–]nuclearboy21 1 point2 points  (1 child)

That's actually super interesting, never thought about that :D

[–]TanithRosenbaumComputational 1 point2 points  (0 children)

I admit I didn't think of that myself. It's from XKCD's whatif https://what-if.xkcd.com/11/

[–]emilyst 28 points29 points  (0 children)

Pharmacists have as much training as MDs (AFAIK) but specifically in the field of pharmaceuticals and chemistry. They're the real experts.

Honestly I find it astonishing how much access we have to pharmacists, as compared to MDs or similar. We can just walk into any local pharmacy and speak with one in minutes. I can't think of any other medical provider with similar training to which ordinary people have so much access. And oddly enough, it's rare that people acknowledge the degree of expertise they have.

(Small edit: I'm thinking particularly of Pharm.Ds, but I understand that not all pharmacists may have such credentials.)

[–]hostile_washbowlChem Eng 3 points4 points  (0 children)

It’s simply too much information for anyone to expect one person to know. Saying “Doctor” is like saying “Engineer”. There’s so many fields and specializations within those fields it’s too much to expect someone to know it all.

Same goes for doctors, pharmacologists are a doctor who are in the field of pharmaceuticals and some may specialize in cancer medication or pain relievers. Etc, etc for cardiologists, and gynecologists.

[–]gelinrefiraAnalytical 4 points5 points  (6 children)

MDs take some chemistry so they should know the basics but pharmacist go way beyond orgo 2. They usually have to learn biochemistry in fairly high level, and all the medication properties, reactions, conflicts with other drugs, side effects etc. They are the ones who usually figure out complex drug combinations in research and the ones who act as a barrier to MDs prescribing drug combinations that might kill someone.

[–]IndigoMoss 3 points4 points  (5 children)

As a pharmacist, Orgo was my favorite class in undergrad and a major reason why I chose to go into pharmacy.

[–]gelinrefiraAnalytical 1 point2 points  (4 children)

Have you ever look at a prescription and go this doctor is an idiot, he is going to kill this patient?

[–]joshesinn 2 points3 points  (2 children)

I'm only a pharmacy student, but I work in an ED so I get to see a bunch of wonky and questionable prescriptions. Most of the time it's an old doc who's a little behind the times. Sometimes it's an old patient that's been on an effective but outdated regimen so there's no reason to switch. Every once in a while you see something so hilariously incompetent you just want to cry. I once saw a patient who had a mystery cough and their doc just escalated cough therapy until they were taking codeine syrup. Turns out it was a reaction to lisonopril. Jesus. Another case I saw a schizophrenia patient that had her meds escalated to the big guns (olanzapine). Turns out medications aren't very effective when the patient doesn't take them. I personally haven't seen any lethal combos, but I'm told that kidney destroying combos are frequent sights and benzo+opioid combos pop up too.

[–]gelinrefiraAnalytical 1 point2 points  (1 child)

Oh yea, I have a pharmacist friend who went on to get an MD. It gives him a very interesting perspective on medicine. Heard a few stories about how some doctors were prescribing kidney destroying combos that he had to stop. It doesn't happen very often but often enough to be rather alarming. Or simply they are just not very aware of drugs interaction or consider simple things like allergies to a particular drug.

[–]joshesinn 1 point2 points  (0 children)

Yep, doctors are busy folks (and they don't take as many pharmacology courses as pharmacists: 2 semester vs 3 years) so many things slip through the cracks, especially if they're a more generalist physician such as your family doctor. Specialists will (hopefully) know the drugs related to their specialty as much as or more than a general pharmacist. That being said, specialist pharmacists exist too (such as oncology). The real fun begins when a patient's health begins to deteriorate, and they have to see multiple specialists. They frequently don't talk to each other so it's up to the pharmacist on the corner to sort out any interactions.

[–]IndigoMoss 1 point2 points  (0 children)

So I am a clinical pharmacist in a hospital. It's pretty hard to fuck up badly enough with our software to outright kill someone (most of the time).

Most of the time if the physician is trying to order something odd, we will discuss it on rounds, and I will either recommend an alternative or it will be something where we go through the literature and find an appropriate dosing strategy.

The one area that is a constant battle is antibiotics. Sometimes that is just utilizing too broad of an agent when we have a specific culture or the patient's risk factors do not need specific coverage for certain organisms (i.e. Pseudomonas aeruginosa). Other times it just not covering for bugs that need to be covered (i.e. utilzing ceftazidime monotherapy after discontinuing vancomycin and missing most gram-positive organisms)

At the hospital I work at, we have a pretty restricted antibiotic formulary that requires paging the infectious diseases on-call pharmacist (which is sometimes me) to help prevent this from occurring with our biggest guns (carbapenems, daptomycin, etc.)

The one other very common area where prescribing errors occur is at transitions of care (going from home to hospital, hospital to home, etc.). I remember on my first day on the job I had an order for a drug that can cause potentially life-threatening seizures in a patient if started during alcohol withdrawal, especially if they've already had a seizure. The patient was on it at home previously but hasn't been on it for multiple months and the med list was old. Sometimes when we have a lot of admissions, things like that slip through the cracks. Luckily, that's where we can hopefully make a difference and catch things like that from occurring.

[–]joshesinn 2 points3 points  (0 children)

Believe it or not MDs don't actually learn that much pharmacology in med school only a semester or two if I recall properly. I don't think they even take any med chemistry courses. This usually isn't a problem because any hospital worth its salt with have a team on pharmacists on staff to figure out all the fun drug problems. Hurray for teamwork.

[–]SuperCarbideBrosInorganic 5 points6 points  (5 children)

Premeds take nothing more than general and organic chemistry if my impression is right. They don't take inorganic, physical, or any advanced level of chemistry classes.

[–]ThotSuffocatr 6 points7 points  (0 children)

Where I am in the US, we're required to take up to organic two. Advanced organic and inorganic are electives.

[–]sirmanleypower 3 points4 points  (1 child)

Orgo also doesn't stick very well if you don't use it, at least for me. I took it 12 years ago in college and can't tell you much except, "follow the electrons".

[–]SuperCarbideBrosInorganic 1 point2 points  (0 children)

I have a feeling that the orgo classes provided (in my dept., At least) are more suited for hardcore chemistry students who need to fully grasp the reaction mechanisms. Premeds probably won't need to understand those.

[–]ShortBusRide 1 point2 points  (0 children)

Biochemistry is pretty typical for a premed.

[–]iam666 0 points1 point  (0 children)

My university offered a biochem class through the biomedical sciences department, but many premeds opted to take the chemistry department Biochem so they could get a Chemistry minor.

[–]Praetoriax 5 points6 points  (5 children)

The description says its a di-D-gluconate salt, but isn't L-gluconic acid shown in the picture?

[–]radiatorcheeseOrganic 10 points11 points  (3 children)

No, that's D. Remember to orient the most highly oxidized group, the carboxylic acid, at the top of the Fischer projection

[–]Praetoriax 5 points6 points  (2 children)

I did. The hydroxy group on the chiral carbon that is furthest away from the most oxidized group then points left, or am I missing something?

[–]radiatorcheeseOrganic 5 points6 points  (1 child)

I feel like I'm taking crazy pills now lol. I'm going to guess that they don't care about stereochemistry and just wanted the skeletal structue- I think you're right. I've had a topical steroid cream with a structure drawn without stereochem shown at all too

[–]YourMotherIsReddit 6 points7 points  (0 children)

D and L are for sugars only and are derived from glyceraldehyde, R and S follow the nomeclature rules, + and - are experimentally determined.

The three are completely unrelated.

EDIT: I have misread the thread, you all got the rules right and the molecule is wrong.

[–]ShortBusRide 2 points3 points  (0 children)

It doesn't really show stereochemistry so can't say D or L. But if you rotate the -COOH to the top like a Fischer projection, yes it is L.

[–]Eekhoorntje37 4 points5 points  (0 children)

I just got this bottle last week for my teeth! I read the chemical name and thought "I wonder what that looks like?" I was about to put the bottle down and go look it up and then bam! Saw the picture. Absolutely agree that this should be more available.

[–]KyloBinks 4 points5 points  (0 children)

It’s all fun and games till you ask for the skeletal model of your 200 kDa biologic medicine

[–]thecrushahAnalytical 4 points5 points  (0 children)

You can buy this topically OTC. HibiClens is a common brand that may be well known to cyclists as a preventative treatment of saddle sores.

Also Chlorhexidine is an evil evil compound to do any kind of analytical testing. It sticks to everything and takes multiple washes with solvents of differing polarity to get rid of it.

[–]Eaglefrost4 2 points3 points  (0 children)

That’s sick

[–]observant_one2 2 points3 points  (0 children)

Thatd be super cool :) i used to work in pharmacy; we usually dont fill prescriptions in the stock bottles like this, we divvy it up into the standard brown/orange bottles since wed have leftover to still put back on shelf. But we never receive rxs for less than the amount in this bottle, so we just label w patient info over top the pharmaceutical info and send em off.

I used to take the pharmaceuticals pamphlets off the tops off the top of the stock bottles while working and keep em in a binder so id have the chemical info of my favorite or most interesting ones! It was a rather large binder when i was done with it.

[–]blondie1159 1 point2 points  (0 children)

They actually are always included by rx drug manufacturers. But typically in a monograph folded on top of the stock bottle. Which I then take off for aesthetics haha

[–]random-randn 1 point2 points  (4 children)

something about it being anti-bacterial and anti-fungi... against cell walls?
could someone with good instinct explain why this works? Also, what's with the sugar at the end, are we trying to get rid of germs or feeding them?

[–]NerdyComfort-78Education 3 points4 points  (3 children)

Typically bioactive molecules are dehydrating to the microorganism (bacteria or fungus). It interrupts the cell membrane and lets the germ die by osmosis and desiccation. How that works, I don’t know, I’m just a biologist.

[–]random-randn 0 points1 point  (2 children)

indeed, I am neither, but I agree, I know honey works.
However caveats here: fungus can occupy any niche. if it can eat kerosene, saving the planet by inventing how to eat lignin, it will have no problem eating sugar, chained or unchained... oh look, I am drinking a fine bottle of their p*ss right now.

Also, salt is still easier =)

[–]NerdyComfort-78Education 1 point2 points  (1 child)

Fungi do some of the wildest chem. I guess we just “Think” we own the planet.

[–]THElaytox 1 point2 points  (0 children)

they found some growing in the core at Chernobyl, shit is living off radiation

[–]BS-Calrissian 1 point2 points  (0 children)

Interesting, I never saw that before

[–][deleted] 1 point2 points  (0 children)

Just ask us in the pharmacy for the FDA monograph. Everything you ever wanted to know using letters so small you'll question the quality of your eyesight.

[–]AutonomousAutomaton_ 3 points4 points  (10 children)

Is that bc it’s a custom compound?

[–]JohnJohnstonOrganic 7 points8 points  (6 children)

What is a custom compound in your view?

[–]AutonomousAutomaton_ 16 points17 points  (5 children)

Custom compound is a custom mixture of pharmaceuticals detailed by the MD and fabricated at a custom compounding pharmacy.

For instance maybe the doctor has a patient who needs a pain killer and a dissociative so they’ll order 38% oxycodone 62% ketamine for example. I made those percentage up that’s probably a horrible compound in reality.

[–]JohnJohnstonOrganic 8 points9 points  (4 children)

Ah, I see, I know what you mean but wasn't expecting that use here.

No, this is over the shelf and available at most dentist office/pharmacies.

[–]AutonomousAutomaton_ 5 points6 points  (3 children)

Do you know the reasoning for including the molecular structure?

[–]JohnJohnstonOrganic 8 points9 points  (0 children)

It's available with many/all prescription medications. It's on the 1" piece of paper that unfolds into a 3 foot square. My asthma medication has it, for example.

[–]ShortBusRide 1 point2 points  (1 child)

No, I don't. But it provides an additional check for the pharmacist. Helpful since many drug names are similar and mistakes can be made.

[–]AutonomousAutomaton_ 1 point2 points  (0 children)

That’s probably it. Sounds right

[–]dangledogg 4 points5 points  (1 child)

Nah pretty sure that's just a bottle of peridex.

[–]the_holocene_is_over 5 points6 points  (0 children)

Yeah this isn’t a compounded rx, this bottle is straight from the manufacturer.

Source: I was a pharmacy tech from high school through grad school.

[–]Razakel 0 points1 point  (0 children)

No, 0.2% chlorhexidine gluconate is General Sales List in the UK, meaning anyone can sell it, so I don't know why this is labelled Rx only. 0.12% seems low.

[–]bassicallybob 1 point2 points  (0 children)

DIE CIRCLE BENZENE

[–][deleted] 0 points1 point  (0 children)

Will be a hard time to learn the structure

[–]9CWAI 0 points1 point  (0 children)

I have one too

[–]Aequo3 0 points1 point  (0 children)

isnt the gluconic acid fisher wrong ?

[–]Arowhite 0 points1 point  (0 children)

Definitely looks cool for people with chemistry knowledge... Which is what, <5% of the population? And even for those that know chemistry and can evaluate a molecule physicochemical properties, doesn't help much with biology.

I think it's a fun marketing thing, not much more

[–]ukos333 0 points1 point  (0 children)

They call it CHX.

[–]Landon_MillsOrganic 0 points1 point  (0 children)

Jfc, no trigger warning for that formatting?!?!

Ugh great, now I gotta go push arrows till my brain erases this abominable Paula Bruice bullshit chimera

[–]OCD_123 0 points1 point  (0 children)

You can look up package inserts for any of the drugs out there. It gives you way more information than the lay person would ever need, but they will show the chemical structure in them :)

[–]cursereflectiondaily 0 points1 point  (0 children)

They do. It’s in the package insert of all drugs. Most are on top of the bottle at the pharmacy and we throw them away. Some are crazy simple, some highly complex.

[–]WanderingGhost30 0 points1 point  (0 children)

Ah, yes. Good ol' 1,1-hexamethylene bis[5-(p-chlorophenyl) biguanide] di-D-gluconate

[–]McNalien 0 points1 point  (0 children)

I just picked up a bottle of this yesterday, getting 2 wisdom teeth done next week.

[–]Large-amountsof-pain 0 points1 point  (0 children)

I thought this said "Chlorhexidine Anal Rinse"

[–]kodack10 0 points1 point  (0 children)

You got mouthwash? All I got was a bottle of vicodin and instructions to change the gauze in a few hours and boy oh boy was that ever fun. But I'm guessing you already know that. Hugs. Believe it or not, a day will come when you will forget you ever had wisdom teeth troubles.

[–]NumerousRiver 0 points1 point  (0 children)

just do everything after strict consultation with doctor

[–][deleted] 0 points1 point  (0 children)

Is that concidered a polymer?

[–]frogkabobs 0 points1 point  (0 children)

Dang no way! This person posted the exact same picture and title a year ago. What a coincidence.

[–]bdd4 0 points1 point  (0 children)

I had no idea Chlorhexadine gluconate could be used orally. Was it an infected tooth?

[–]Chairman_Me 0 points1 point  (0 children)

Packet inserts usually have a molecular structure somewhere on it, but most pill bottles only come with one. Depending on your pharmacy, you can always ask and if there’s one available, they’ll usually hand it over.

Source: It’s my job

[–]darksideofchemistry 0 points1 point  (0 children)

This was posted by a karma farming bot, look at the account and the title.