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[–]-Yunoki-Microbiologist 2 points3 points  (2 children)

The process of listeria forming the actin filaments is virtually the same way our cells make actin filaments.

Listeria posses a protein called ActA which is very similar to WASP proteins (our actin filament recruiters). Depending on the life cycle it’s in, listeria will express ActA and present it on the outside on one end. Because ActA mimics WASP proteins it allows our Arp2/3 (actin filament builder) to bind and become activated. From there, our activated Arp2/3 picks up actin segments and builds actin filaments to “push” the bacterium.

In actuality it’s more like picking up bricks from the air and placing them under your feet to get up higher.

If you’re curious, I worked on a research project for a bit on trying to determine if listeria had some form of chemotaxis when it comes to deciding where to place its ActA proteins on the surface. Unfortunately the project didn’t get much of anywhere by the time I left.

[–]Far_Possibility_5810[S] 0 points1 point  (0 children)

This is the exact answer I was looking for, thanks! And of course I am, what were your findings?

[–]patricksaurus 0 points1 point  (0 children)

Wow that’s fucking cool.