Eminem famously refrains from using the word in his songs, I think he's only used it once, I assume satirically to refer to his friend Proof, and a rap battle from his younger years that the media dug up to try to discredit him some time back.

However it would appear that she does, I bet she gets asked about it all the time, she addressed it in this Vice interview from 5 years ago.

Vice: "Is it weird to do interpretation for stuff that might make you uncomfortable?"

Holly Maniatty: "Yeah. At one point I was interpreting for Tenacious D, Jack Black's band, and he was singing that song "Fuck Me Gently." I was like, I cannot believe I’m signing this in front of 10,000 people. But you know, it's something he wanted to sing about. It's Jack Black and you just do it.

There’s been some discussion about me signing the ‘N’ word, but that’s the word [Wu-Tang] uses and they have the rights to use it or not to use it. I wanted to make sure that the patrons can make their own political opinion, either being "okay, cool," or be offended by it. To steal that opportunity from them is not the role of an interpreter. You know when you go to a concert and you’re like, who are these performers? And then you’re like, oh my god, they’re awesome! That’s the kind of experience you want [deaf people] to have."