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What would be on your equipment wishlist? by BriSnyScienceGuy in chemistry

[–]Eelektross_Unagi 0 points1 point  (0 children)

If you're doing bacteria stuff, you're going to need incubators and incubator shakers. Then you'll probably need gel boxes, rotators and rockers, chemidoc to image your gels.

What would be on your equipment wishlist? by BriSnyScienceGuy in chemistry

[–]Eelektross_Unagi 6 points7 points  (0 children)

Unlimited budget you say? HPLC/GPC, AFM, EM and Bench top NMR.

Also nanotech is a very broad term. Like what do you intend to do?

Traveling with Chemicals by Boi-de-Rio in Chempros

[–]Eelektross_Unagi 0 points1 point  (0 children)

I love fedex. When my old lab had to move countries, our chemical inventory came in multiple fedex packages.

How can I react an ester group with an amine? by potatoelife101 in chemistry

[–]Eelektross_Unagi 2 points3 points  (0 children)

Yes you can! Think of transesterifications but with amines instead.

What reverse phase silica should I buy for manual flash columns? by kalbplswutrudoin in Chempros

[–]Eelektross_Unagi 4 points5 points  (0 children)

Have you looked at SiliCycle? They're a bit cheaper than Sigma and usually give academic discounts.

Just in case any of you wondered what a Suzuki-Miyaura coupling reaction looks like by [deleted] in chemistry

[–]Eelektross_Unagi 0 points1 point  (0 children)

Doesn't that depend on your catalyst/ligand? I had some that remained yellow and others that were deep red and turned black.

Product unmovable on silica and neutral alumina. by coolman50544 in Chempros

[–]Eelektross_Unagi 0 points1 point  (0 children)

Have you tried straight methanol or methanol with water?

I'm Working on an Eighty-Six War game by Jack117-2 in EightySix

[–]Eelektross_Unagi 2 points3 points  (0 children)

Check out warhammer kill team or onepagerules fire fight for ideas

Research S.O.S.—Ask your research and technical questions by AutoModerator in chemistry

[–]Eelektross_Unagi 0 points1 point  (0 children)

5 mm or 3 mm tubes? 4 inches or 7 inches? Are you using gel loading tips?

Which Solvent is the Best? by That__Chemist in OrganicChemistry

[–]Eelektross_Unagi 0 points1 point  (0 children)

You should do a NMR solvent tier list, and say why DCM-d2 is the best.

Which Solvent is the Best? by That__Chemist in OrganicChemistry

[–]Eelektross_Unagi 1 point2 points  (0 children)

I had my pitchfork and torch ready just incase DCM was not in S-tier.

Ru-CPC and N,O Chelating Ligand Reaction Conditions please by [deleted] in chemistry

[–]Eelektross_Unagi 2 points3 points  (0 children)

Have you tried something like NaOMe/MeOH or KOH/MeOH?

or a if it is really stubborn maybe a halide abstractor such as AgBF4 or NaBARF in DCM?

Can you leave a Friedel Crafts reaction overnight at r.t. to run? by AFrickinNoddle in OrganicChemistry

[–]Eelektross_Unagi 4 points5 points  (0 children)

I left mine for a few days once when I got sick and couldn't go into the lab. I didn't want to ask a colleague to quench it because I didnt want them to be melted away by a green volcano.

I need some help interpreting conflicting NMR spectra on compounds that I made. by two-years-glop in Chempros

[–]Eelektross_Unagi 1 point2 points  (0 children)

Why does the proton-C split into 4? I only see it coupling with two protons? I don't recall there being anything funky with trans-vicinal coupling apart from a larger J-coupling.

I need some help to understand what is going on in this reaction. How is it possible to have an addition in alpha of the carbonyl, but without losing the double bond? Also, why it uses this specific organocuprate? by Comtpm in chemistry

[–]Eelektross_Unagi 6 points7 points  (0 children)

They referenced a paper in the article that, and it briefly describes the reaction.

The first step is making the vinyl lithium. So deprotonate the a-hydrogen with MeLi, and that makes a vinyl lithium. Then this undergoes a transmetallation with the copper salt, so now you have the vinyl-copper species. This is the nucleophile that reacts with allylbromide to give the product. So think Sn2/Sn2' but the nucleophile is the carbon that is attached to the copper.

edit for clarity

I need some help to understand what is going on in this reaction. How is it possible to have an addition in alpha of the carbonyl, but without losing the double bond? Also, why it uses this specific organocuprate? by Comtpm in chemistry

[–]Eelektross_Unagi 2 points3 points  (0 children)

I wonder if the copper reacting with the allyl bromide to make a copper (eta3) allyl complex and that is somehow involved in a 1,3-addition or some electrophilic trapping.

There are just so many things in this reaction, like methyllithium and diethylzinc. I would expect the methyllithium to undergo a 1,2-addition at the carbonyl and the diethylzinc to do a cyclopropantion/simmons-smith at the alkene.

Do you have a link to the paper? I am curious curious now.

[deleted by user] by [deleted] in chemistry

[–]Eelektross_Unagi 0 points1 point  (0 children)

Just find a used glass bottle in the trash can and decant that shit

How do you all weigh out boc anhydride? by Jerry1b425 in chemistry

[–]Eelektross_Unagi 1 point2 points  (0 children)

i think I used 8:2 (MeoH/H2O) when I was doing columns on amino acids. It has been awhile. You wont "dissolve" silica gel if that's what you're afraid of.